EB Simplex-migratory circinate

      EB Simplex-migratory circinate is another rare autosomal dominant form of EB Simplex. It is due by a mutation in the keratin 5 gene. There is widespread blistering seen at birth.
     The characteristic feature is the development of patches of erythema (readness) taht appear to "migrate" on the skin, leaving behind hyperpigmentation or brown discoloration of the skin. Milia and scarring typically do not occur. Dental enamel is normal. Blistering of the mouth does not occur.
     Affected people typically do not develop poor growth,anemia, or problems with the trachea/respiratory tract, intestines/gastrointestinal tract, eyes or genitourinary tract.